Cholinesterase activity of motor end plate in human skeletal muscle
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چکیده
منابع مشابه
Cholinesterase activity of motor end plate in human skeletal muscle.
The activity and properties of cholinesterase of the motor end plate in human intercostal muscle were studied in the isolated muscle membrane. This preparation was used because cholinesterase activity of the membrane preparation was localized in the motor end plate without contamination of cholinesterase of other muscle components. Under the experimental conditions, cholinesterase in a human en...
متن کاملMotor endplate cholinesterase in human skeletal muscle.
The activity and properties of cholinesterase (ChE) of the motor endplate and its fractions were studied in isolated human skeletal muscle. This preparation was used since the ChE activity of the membrane preparation was localized only in the motor endplate. The endplate ChE was stable in the isolated membrane for 4 weeks at 4 degrees C. The specific activity of the extracted ChE of human muscl...
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Usually mathematicians use Hodgkin-Huxley model or FitzHug-Nagumo model to simulate action potentials of skeletal muscle fibers. These models are electrically excitable, but skeletal muscle fibers are stimulated chemically. To investigate skeletal muscle fibers we use a model with six ordinary differential equations. This dynamical system is sensitive to initial value of some variables so it is...
متن کاملCholinesterase in normal and abnormal human skeletal muscle.
The original theory of neurqmuscular transmission involving acetylcholine led to the necessity to postulate an enzyme which hydrolysed it. This was done by Dale in 1914. It was not until 1932, however, that Stedman, Stedman, and Easson were able to prepare from horse serum an enzyme which could actually do this and which was called cholinesterase. The enzyme was then found to be present in a wi...
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Regarding the motor end plates, the earliest evidence of the formation of such structures was observed in the muscle of foetuses of nine and ten weeks development. At this stage the developing motor end plate consits of several small axons covered on their outer aspect by Schwann cell cytoplasm, while on the inner aspect they are separated by a layer of basement membrane of the myotube with whi...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1970
ISSN: 0021-9738
DOI: 10.1172/jci106313